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What is the most typical clinical form of a pseudotuberculosis?
The most common clinical Y pseudotuberculosis syndromes are self-limited enterocolitis and mesenteric lymphadenitis (pseudoappendicitis), but septicemia may occur in immunocompromised hosts, resulting in metastatic infection.
What are the symptoms of Yersinia enterocolitica?
Symptoms of Y enterocolitica infection typically include the following:
- Diarrhea - The most common clinical manifestation of this infection; diarrhea may be bloody in severe cases.
- Low-grade fever.
- Abdominal pain - May localize to the right lower quadrant.
- Vomiting - Present in approximately 15-40% of cases.
What is the main factor in pathogenesis of a pseudotuberculosis?
The enteropathogen, Yersinia pseudotuberculosis, requires a large inoculum to produce the disease. The primary virulence factor is a plasmid-encoded protein that causes increased invasiveness. Yersinia pseudotuberculosis survives intracellularly.
How is Yersinia enterocolitica treated?
Care in patients with Y enterocolitica infection is primarily supportive, with good nutrition and hydration being mainstays of treatment. First-line drugs used against the bacterium include aminoglycosides and trimethoprim-sulfamethoxazole (TMP-SMZ).
What is the reservoir of pseudotuberculosis?
pseudotuberculosis has its natural reservoirs in farm animals, wild rodents, rabbits, deer , and birds, including turkeys, ducks, geese, pigeons, pheasants, and canaries. It is transmitted among animals by the fecal-oral route.
How did Yersinia pestis evolve?
pestis is known to have evolved from the relatively mild gut pathogen Yersinia pseudotuberculosis sometime within the last 5,000 to 10,000 years – very recently on an evolutionary timescale.
Does Yersinia pestis have flagella?
Yersinia pestis is nonmotile. Other species are nonmotile at 98.
How do I know if I have Yersinia pestis?
I. Yersinia pestis is a nonmotile, slow-growing, facultative organism classified in the family Enterobacteriaceae. It appears as plump, gram-negative coccobacilli that are seen mostly as single cells or pairs, which may exhibit bipolar staining from a direct specimen if stained with Wright stains.
How is Yersinia pestis harmful?
As Yersinia pestis can be easily obtained and cultured and is highly pathogenic for humans, it poses a serious threat of being used for bioterrorism purposes. Artificially created aerosol containing plague bacilli can cause numerous and almost simultaneous cases of primary pulmonic plague in an exposed population.
What pandemic happened in 1717?
1717: Blizzards, Blackbeard and a band on a barge In late February and early March, a series of blizzards covered the Virginia and New England colonies in 5 feet of snow, with drifts up to 20 feet deep.
How many people died in the last pandemic?
For those living through the pandemic, which killed 50 million people worldwide, flu gave the impression of being an indiscriminate killer, just as the Black Death had 600 years before.
What supplies should you have for a pandemic?
You can prepare now by creating a stockpile of emergency supplies. Experts recommend you have at least a one-week stockpile of food, water, and goods purchased over time to limit the financial impact and prevent store shortages. Seal water containers tightly, label them with a date and store in a cool, dark place.
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