Where is Yersinia pestis found?

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Where is Yersinia pestis found?

The organism that causes plague, Yersinia pestis, lives in small rodents found most commonly in rural and semirural areas of Africa, Asia and the United States. The organism is transmitted to humans who are bitten by fleas that have fed on infected rodents or by humans handling infected animals.

Does Yersinia pestis still exist?

An outbreak of the bubonic plague in China has led to worry that the “Black Death” could make a significant return. But experts say the disease isn't nearly as deadly as it was, thanks to antibiotics.

What kills Yersinia pestis?

Aminoglycosides: streptomycin and gentamicin Streptomycin is the most effective antibiotic against Y. pestis and the drug of choice for treatment of plague, particularly the pneumonic form (2-6).

What cured the Black Plague?

Treatment. Several classes of antibiotics are effective in treating bubonic plague. These include aminoglycosides such as streptomycin and gentamicin, tetracyclines (especially doxycycline), and the fluoroquinolone ciprofloxacin.

Who found the cure for the Black Plague?

Credit for discovering the bacterial cause of plague is accorded to the French physician Alexandre Yersin (1863–1943), for his bacteriological investigations in June 1894 in Hong Kong during a deadly epidemic [32].

When did the Black Death End?

1346 – 1353

What was the first pandemic?

The earliest recorded pandemic happened during the Peloponnesian War. After the disease passed through Libya, Ethiopia and Egypt, it crossed the Athenian walls as the Spartans laid siege. As much as two-thirds of the population died. The symptoms included fever, thirst, bloody throat and tongue, red skin and lesions./span>

How long did Spanish flu outbreak last?

The Spanish flu, also known as the 1918 influenza pandemic, was an unusually deadly influenza pandemic caused by the H1N1 influenza A virus. Lasting from February 1918 to April 1920, it infected 500 million people – about a third of the world's population at the time – in four successive waves.

Was there a smallpox pandemic?

The last major smallpox epidemic in the United States occurred in Boston, Massachusetts throughout a three-year period, between 1901 and 1903. During this three-year period, 1596 cases of the disease occurred throughout the city. Of those cases, nearly 300 people died.

Who cured smallpox?

Edward Jenner (Figure ​1) is well known around the world for his innovative contribution to immunization and the ultimate eradication of smallpox (2).

When was the last smallpox pandemic?

Thousands of years ago, variola virus (smallpox virus) emerged and began causing illness and deaths in human populations, with smallpox outbreaks occurring from time to time. Thanks to the success of vaccination, the last natural outbreak of smallpox in the United States occurred in 1949.

Why did smallpox kill so many?

The cause of death from smallpox is not clear, but the infection is now known to involve multiple organs. Circulating immune complexes, overwhelming viremia, or an uncontrolled immune response may be contributing factors. In early hemorrhagic smallpox, death occurs suddenly about six days after the fever develops.

Did anyone survive smallpox?

Smallpox was a terrible disease. On average, 3 out of every 10 people who got it died. People who survived usually had scars, which were sometimes severe.

What started smallpox?

Early Victims. Smallpox is thought to have originated in India or Egypt at least 3,000 years ago. The earliest evidence for the disease comes from the Egyptian Pharaoh Ramses V, who died in 1157 B.C. His mummified remains show telltale pockmarks on his skin.

What animal started Ebola?

Scientists do not know where Ebola virus comes from. However, based on the nature of similar viruses, they believe the virus is animal-borne, with bats or nonhuman primates (chimpanzees, apes, monkeys, etc.) being the most likely source.

What if smallpox came back?

because if everyone forgets, the world may not take the appropriate steps to prevent smallpox from returning. Smallpox returning could result in blindness, terrible disfigurement and death for millions or even billions./span>

What did smallpox do?

People who had smallpox had a fever and a distinctive, progressive skin rash. Most people with smallpox recovered, but about 3 out of every 10 people with the disease died. Many smallpox survivors have permanent scars over large areas of their body, especially their faces. Some are left blind.

Is chickenpox related to smallpox?

Chickenpox is the most important disease likely to be confused with smallpox. It is caused by a different virus. In smallpox, fever is present for 2 to 4 days before the rash begins, while with chickenpox, fever and rash develop at the same time.

Can smallpox be cured?

There is no cure for smallpox, but vaccination can be used very effectively to prevent infection from developing if given during a period of up to four days after a person has been exposed to the virus. This is the strategy that was used to eradicate the disease during the 20th century./span>

What does smallpox mean?

: an acute contagious febrile disease of humans that is caused by a poxvirus (species Variola virus of the genus Orthopoxvirus), is characterized by a skin eruption with pustules, sloughing, and scar formation, and is believed to have been eradicated globally by widespread vaccination.

How did smallpox kill?

Researchers have solved a fundamental mystery about smallpox that has puzzled scientists long after the natural disease was eradicated by vaccination: they know how it kills us. Scientists can now describe how the virus cripples immune systems by attacking molecules made by our bodies to block viral replication./span>

Is Smallpox a plague?

For centuries smallpox was one of the world's most-dreaded plagues, killing as many as 30 percent of its victims, most of them children. Those who survived were permanently immune to a second infection, but they faced a lifetime of disfigurement and in some cases blindness.

Is there any smallpox left?

Currently, there is no evidence of naturally occurring smallpox transmission anywhere in the world. Although a worldwide immunization program eradicated smallpox disease decades ago, small quantities of smallpox virus officially still exist in two research laboratories in Atlanta, Georgia, and in Russia.